NRXN3, neurexin 3, 9369

N. diseases: 64; N. variants: 29
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10136360
rs10136360
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0337443
Disease:
Sodium measurement 		G 0.700 GeneticVariation GWASCAT GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits. 31409800 2019
dbSNP: rs10150332
rs10150332
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs11621908
rs11621908
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0424574
Disease:
Duration of sleep 		T 0.700 GeneticVariation GWASCAT Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. 30804565 2019
dbSNP: rs11621908
rs11621908
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0424574
Disease:
Duration of sleep 		C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. 30846698 2019
dbSNP: rs11849937
rs11849937
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0270496
Disease:
Schizoaffective disorder, bipolar type 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
dbSNP: rs17109256
rs17109256
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs17109256
rs17109256
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0205682
Disease:
Waist-Hip Ratio 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005890
Disease:
Body Height 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs7144011
rs7144011
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs72690737
rs72690737
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs8009329
rs8009329
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs8019381
rs8019381
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE We found that the SNP rs8019381 of NRXN3 that is located adjacent to splicing site #5 (SS#5) interacts with the APOE ε4 haplotype and alters NRXN3 transmembrane or soluble isoform expression in AD postmortem cortex. 30902061 2019
dbSNP: rs12882688
rs12882688
Entrez Id: 9369;112268125
Gene Symbol: NRXN3;LOC112268125
NRXN3;LOC112268125
CUI: C0596887
Disease:
mathematical ability 		A 0.700 GeneticVariation GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
dbSNP: rs2370901
rs2370901
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs7144011
rs7144011
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		G 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs7144011
rs7144011
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
dbSNP: rs7157669
rs7157669
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0019569
Disease:
Hirschsprung Disease 		0.010 GeneticVariation BEFREE Several SNPs were significantly associated with altered risk of HD in the Chinese Han population, including rs1421589 within <i>NRXN1</i>, rs11795613 and rs4844285 within <i>NLGN3,</i> as well as rs5961397, rs7157669 and rs724373 within <i>NLGX4X</i> (all P<0.05). 29622757 2018
dbSNP: rs724373
rs724373
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0019569
Disease:
Hirschsprung Disease 		0.010 GeneticVariation BEFREE Several SNPs were significantly associated with altered risk of HD in the Chinese Han population, including rs1421589 within <i>NRXN1</i>, rs11795613 and rs4844285 within <i>NLGN3,</i> as well as rs5961397, rs7157669 and rs724373 within <i>NLGX4X</i> (all P<0.05). 29622757 2018
dbSNP: rs10146997
rs10146997
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.700 GeneticVariation GWASCAT An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. 28566273 2017
dbSNP: rs17109221
rs17109221
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0005910
Disease:
Body Weight 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs2370982
rs2370982
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C0037369
Disease:
Smoking 		T 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. 28443625 2017
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C4049938
Disease:
Physical Activity Measurement 		T 0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500 2017
dbSNP: rs7141420
rs7141420
Entrez Id: 9369
Gene Symbol: NRXN3
NRXN3
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500 2017